Eif3b and bladder cancer

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August undefined, 2024

WebNov 1, 2024 · • Screened for genes that alter drug response in bladder cancer using RNAi and next-generation sequencing. ... AGL and eIF3b) … WebNov 13, 2024 · Regarding subunit b (eIF3b), its high expression has been observed in both human bladder and prostate tumors and correlates to cancer prognosis. 68 In fact, upregulation of eIF3b expression can be associated with stage, grade, and outcome in patients with these cancers. 68 Moreover, depletion of eIF3b inhibits cancer cell growth …

Eukaryotic Translation Initiation Factor 3b is both ... - Journal of …

WebApr 10, 2013 · Search worldwide, life-sciences literature Search. Advanced Search WebRecent studies have shown that the expression of the eIF3b subunit is elevated in bladder and prostate cancer, and eIF3b silencing inhibited glioblastoma growth and induced … laboratory chemical resistant gloves

Translation initiation factor eIF3b expression in human cancer and …

WebFeb 22, 2024 · Wang et al. proved that EIF3B is upregulated in prostate and bladder cancer tissues and that it promotes bladder and prostate cancer growth and lung … WebMay 15, 2024 · Additionally, as an important part of the EIF3 complex, EIF3B is also widely known for its involvement in tumor formation. For instance, Wang et al. found that the silencing of EIF3B gene expression inhibited the proliferation of colon cancer cells . In summary, the vast preiously reported mechanism studies gave the clue of m6A … WebEIF3B. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. … laboratory chemist

Effects of EIF3B gene downregulation on apoptosis and proliferation …

Subcellular - EIF3B - The Human Protein Atlas

WebSep 1, 2024 · This study aimed to evaluate the effect of eukaryotic initiation factor 3B (EIF3B) downregulation on cell proliferation, apoptosis, migration, invasion and the β-catenin pathway in endometrial cancer. EIF3B mRNA and protein expressions were determined in human endometrial cancer cell lines (Ishikawa, HEC-1A, RL95-2 and EFE-184) and in … WebJun 15, 2024 · Prostate cancer, the second most common cancer among male adults, affects millions globally. We sought to investigate the expression and contribution of Eukaryotic translation initiation factor 3 subunit b (EIF3B) in prostate cancer. Expression of EIF3B was analyzed in both human prostate patient tissues and prostate … promo code for thriftbooksWebApr 15, 2012 · Abstract. The initiation of translation in eukaryotes is promoted by multi-protein eukaryotic initiation factor complexes (eIFs). While several eIF subunits are overexpressed in cancer, very few have been conclusively implicated as drivers of human cancer phenotypes. Through a transcriptomic analysis of human bladder cancer our … laboratory chemical life cycle

"WebSep 19, 2024 · Patients with advanced bladder cancer have poor outcomes, indicating a need for more efficient therapeutic approaches. ... (EIF3B) expression elevated in human … " - Eif3b and bladder cancer

Eif3b and bladder cancer

Translation Initiation Factor eIF3b Expression in Human Cancer …

WebAug 19, 2024 · Eukaryotic translation initiation factor 3 (eIF3) plays an important role in the regulation of mRNA translation, cell growth and cancer development. eIF3b is the main scaffolding subunit in the ... WebAug 1, 2024 · This finding could be explained by that: EIF3B might promote cell proliferation and repress cell apoptosis via downregulating the apoptosis inhibitory protein such as B cell leukemia/lymphoma 2...

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WebApr 19, 2024 · Bladder cancer signs and symptoms may include: Blood in urine (hematuria), which may cause urine to appear bright red or cola colored, though … WebApr 10, 2013 · Depletion of eIF3b inhibits bladder cancer cell growth by inhibition of G1/S transition of the cell cycle (A) eIF3b was depleted by eIF3b siRNAs (oligos eIF3b-3 and eIF3b-4) in UMUC3 and Lul2 human bladder cancer cells. Cell growth was evaluated over five days by the alamarBlue assay. Data shown is the mean ± S.D. of fluorescence …

WebThe Expression pattern of EIF3B in Breast Cancer (TCGA, HPA, IHC, RT-PCR and WB) (a) EIF3B mRNA expression in 112 pairs of breast cancer tissues and matched non-cancer … WebOct 15, 2024 · Additionally, up-regulation of EIF3B correlates with poor disease-specific survival in patients with bladder cancer . Even though …

WebBackground: Eukaryotic translation initiation factor 3B (eIF3b) has been reported to be overexpressed in colon, bladder and prostate cancers as well as in glioblastoma. However, there is no report on any correlation of eIF3b gene expression with cell proliferation and apoptosis in chronic myeloid leukemia (CML). Objectives: In ... WebAbstract. Background/aim: Urothelial carcinoma (UC) of the urinary bladder is the second most common tumor in the field of urology and is characterized by a relatively aggressive …

WebSep 22, 2015 · A bladder cancer patient-derived xenograft displays aggressive growth dynamics in vivo and in organoid culture Elise Y. Cai Jose Garcia Hung-Ming Lam Scientific Reports (2024) Download PDF...

WebThe oncogenic role of EIF3B has been widely reported in gastric cancer [11], esophageal carcinoma [12] and bladder cancer [13]. ... Eukaryotic translation initiation factor 3 subunit B... laboratory chemical storage expiryWebSep 3, 2024 · In addition, its expression related to human bladder and prostate cancer prognosis and was required for tumor growth . ... Wang H, Ru Y, Sanchez-Carbayo M, … promo code for think energyWebJun 4, 2012 · Through a transcriptomic analysis of human bladder cancer our studies suggested that eIF3b, considered to be the major scaffolding subunit within the eIF3 … laboratory chemist jobsWebCancer type Any Bile duct cancer Bladder cancer Bone cancer Brain cancer Breast cancer Cervical cancer Colorectal cancer Esophageal cancer Gallbladder cancer Gastric cancer Head and neck cancer Kidney cancer Leukemia Liver cancer Lung cancer Lymphoma Myeloma Neuroblastoma Non-cancerous Ovarian cancer Pancreatic cancer … laboratory chemical suppliers in vadodara laboratory chemical safety summariesWebJan 1, 2024 · Four cell lines were analyzed for expression of EIF3B mRNA using quantitative PCR assay which showed that the EIF3B gene is highly expressed in all tested cell lines in comparison with IOSE80 ().Ovarian cancer cell line SKOV3 and HO-8910 with relatively high expression of EIF3B mRNA was selected and their EIF3B genes were … laboratory chemical hygiene plan sampleWebSep 1, 2024 · EIF3B was strongly expressed in malignant melanoma tissues and cells. A, B, The protein levels of EIF3B in 164 cases of malignant melanoma tumor tissues and 26 cases of paracarcinoma tissues were determined by immunohistochemical staining. laboratory chemistry tests costs