Chemotherapy platinum agents

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August undefined, 2024

WebApr 11, 2024 · Compared with using chemotherapy alone, anti-angiogenic agents, targeted therapy, and immunotherapy can provide more benefits in survival rate for recurrent platinum resistance. Although various anti-cancer agents are used in treating recurrent platinum-resistant ovarian cancer, there is no consensus on the international standards … WebChemo drugs can be grouped by how they work, their chemical structure, and their relationships to other drugs. Some drugs work in more than one way, and may belong to more than one group. ... Lo Vullo S, et al. Impact of the number of cycles of platinum …

Hypersensitivity Reactions Associated with Platinum …

WebCisplatin, a chemotherapy drug, is best known for curing testicular cancer. It is also used in the treatment of a wide range of other cancers, including lung, bladder, cervical, and ovarian cancers. Cisplatin and other similar … WebAug 21, 2024 · At present, the first-line chemo for OC is on the basis of the combined use of platinum-derived cytotoxic agents and paclitaxel. Despite high response rate and median PFS, over 70% of these patients would finally suffer disease progression. The emergency of resistance to platinum-resistant chemo mainly accounts for the deaths with recurrent OC. right point study abroad

List of chemotherapeutic agents - Wikipedia

WebAlthough platinum-based chemotherapy regimen is regarded as the gold standard for treating advanced UC patients, 57 there is no established treatment for these patients with progressive disease other than the first-line platinum-based chemotherapy. Due to the … WebHence, Pt drugs may still be part of the standard of care for several cancers in the coming years. Platinum chemotherapy agents remain among the most widely used anticancer drugs, but there is ... The first platinum-based chemotherapy drug, cisplatin, was approved for use by the FDA in 1978Trusted Source. Researchers are continuing to examine newer drugs that may cause fewer side effects. See more Platinum-based chemotherapy drugs can cause serious complications, such as cognitive changes or cardiovascular problems. Your doctor may recommend lowering your dose or stopping treatment if you develop severe … See more Researchers are continuing to examine whether platinum-based chemotherapy is safe for people who are pregnant or breastfeeding. In a small 2024 study, researchers found evidence that it might be reasonably safe … See more According to the American Cancer SocietyTrusted Source, it’s generally not recommended to receive a vaccine during chemotherapy or radiation treatment. The exception is the flu … See more A dose-limiting side effect is a side effect that’s serious enough to prevent doctors from increasing the dose of the drug further. The dose-limiting side effect of cisplatin is nephrotoxicity, the deterioration of your kidney … See more right point sealants

Inclusion of Platinum Agents in Neoadjuvant …

WebMar 19, 2014 · Introduction. Chemotherapy drugs used to treat cancer can be neurotoxic by either exerting a direct noxious effect on the brain or the peripheral nerves. 1, 2 Nonetheless, chemotherapy-induced peripheral neurotoxicity (CIPN) is considered to be among the most common non-hematological adverse effects of a number of effective … WebOct 22, 2024 · A 2024 study notes that platinum-based chemotherapy drugs are associated with about 40 different side effects, ranging from nausea and vomiting to anaphylaxis (severe allergic reaction) and cytopenia. right pointerWebChemotherapy for Breast Cancer. Chemotherapy (chemo) uses anti-cancer drugs that may be given intravenously (injected into your vein) or by mouth. The drugs travel through the bloodstream to reach cancer cells in most parts of the body. Sometimes, if cancer spreads to the spinal fluid, which surrounds and cushions the brain and spinal cord ... right pointing arrow clip art

"WebDec 21, 2024 · Platinum (Pt) agents, usually referring to carboplatin (Cb) and cisplatin(DDP), are cytotoxic DNA-damaging chemo-drugs widely used in various malignancies. Platinum can cause DNA strand breaks ... " - Chemotherapy platinum agents

Chemotherapy platinum agents

Platinum-Based Chemotherapy: Uses, Effectiveness, Side …

WebFeb 7, 2024 · Platinum-based drugs cisplatin, carboplatin, and oxaliplatin are widely used for chemotherapeutic eradication of cancer. However, the side effects of platinum drugs, such as lack of selectivity, high systemic toxicity, and drug resistance, seriously limit their clinical application. With advancements in nanotechnology and chemical synthesis, Pt ... WebSep 29, 2024 · 1 INTRODUCTION. Chemotherapeutic drugs have been used in the treatment of neoplasms since the 1940s. 1, 2 Many types of antineoplastic agents were introduced in clinical practice and, despite the great diffusion of biological agents, chemotherapy (CHT) still represents the gold standard for the treatment of the majority …

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WebChemotherapy is the use of drugs to destroy cancer cells. This type of cancer treatment works by keeping cancer cells from growing, dividing, and making more cells. Chemotherapy can be used as a treatment for many different cancers. Your doctor may refer to chemotherapy as standard chemotherapy, traditional chemotherapy, or … Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer. Their active moieties are coordination complexes of platinum. These drugs are used to treat almost half of people receiving chemotherapy for cancer. In this form of chemotherapy, commonly used drugs include cisplatin, oxaliplatin, and carboplatin, but several have been proposed or are under development. Addition of platinum-based chemotherapy drugs to chemor…

WebPlatinum drugs are important components of multiagent chemotherapy regimens for numerous malignancies, including sarcomas, and tumors of the testes, ovary, bladder, lung, brain, head and neck, and others (Kelland, 2007). Cisplatin is known to produce … WebMay 15, 2024 · The platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective, their use is limited by their severe, dose-limiting side effects (also referred to as adverse …

WebApr 4, 2024 · Oxaliplatin is a cytotoxic chemotherapy drug used to treat cancer. It is a type of platinum drug and an alkylating agent. Like other alkylating agents, oxaliplatin works by interfering with the development of DNA in a cell. It … Webplatinum-based chemotherapy. However, the toxicity of che-motherapy inﬂuences further therapy and even survival time. We concluded that polymorphisms of CASP8 contribute to the prognosis of advanced lung adenocarcinoma patients treated with …

WebPlatinum-based chemotherapy agents including carboplatin (Paraplatin®), cisplatin (Platinol®), and oxaliplatin (Eloxatin®), are used for the treatment of various cancer types. Platinum chemotherapy is not FDA approved for the treatment of prostate cancer; however, it is sometimes used in very advanced prostate cancer patients who have ... right point of impactWebThe platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective, their use is limited by their severe, dose-limiting side effects (also referred to as adverse effects/events). In total, a cancer … right posterior hepatic notch signWebMay 20, 2010 · Platinum-containing chemotherapy agents (cisplatin, carboplatin, oxaliplatin) have been approved in the first-line setting of numerous malignancies, such as ovarian, bladder, head and neck, colorectal, and lung cancer. Their extensive use over the last decade has led to a significant increase in the incidence of hypersensitivity reactions, … right pointing chevronWebChemotherapy-associated PRES is an increasingly encountered syndrome. Both neurologists and non-neurologists should be familiar with the most commonly implicated agents, symptoms, risk factors, and clinical course of chemotherapy-associated PRES, given its favorable prognosis with appropriate manage … right politicsWebUsually, the combination includes a type of chemo drug called a platinum compound (usually cisplatin or carboplatin), and another type of chemo drug called a taxane, ... Some chemo drugs may have long-term or even permanent side effects: Cisplatin can cause kidney damage. To help prevent this, doctors give lots of IV fluid before and after this ... right pointed arrowWebNov 1, 2004 · These classes of drugs include the anthracyclines, most alkylating agents, platinum-coordination complexes, epipodophyllotoxins, and camptothecins. For these drugs, the hepatic microsomal monooxygenase system is a primary site where ROS are generated, although other enzymatic (e.g., xanthine oxidase) and nonenzymatic (Fenton … right pointing triangleWebplatinum-based chemotherapy. However, the toxicity of che-motherapy inﬂuences further therapy and even survival time. We concluded that polymorphisms of CASP8 contribute to the prognosis of advanced lung adenocarcinoma patients treated with platinum-based chemotherapy. And we think polymorphisms of CASP8 may be … right pointing finger